GBS Leiden: innovative solutions from concept to trials
GBS is CRO also focused on participating in and performing large cohorts population and clinical observational studies that aim to identify circulating biomarkers for the occurrence of disease and as well as discovery of circulating prognostic factors that alter the outcomes of disease.
Concept stage
- ● Assessing feasibility
- ● Selecting the most appropriate readouts, biomatrices and functional assays
- ● Awareness of pre-analytical requirements
- ● Sourcing additional samples¨Iterative study plans
- ● Identifying most cost-effective solutions
Sample collection and storage
- ● Protocols for sample collection, including sample collection kits
- ● Serum/plasma processing
- ● Cell isolation
- ● DNA/RNA isolation
- ● 24/7 monitored facilities and equipment
Laboratory analysis
- ● ELISA based platforms
- ● Multiplex platform
- ● Enzymatic activity assays
- ● Functional cell-based assays
- ● Biochemical assays
- ● Flow cytometry, cell separation
- ● Mitochondrial function
- ● Assay validation and performance reported by FDA/EMA guidelines
- ● Data formatted to your database requirements
Study Analysis
- ● Software and statistical support
- ● Data interpretation
- ● Pre-validation and final reports
- ● Publication support
Our know-how approach and flexibility ensures tailoring of the screening method to accommodate the novel approaches for obtaining, storing and analyzing data through biomedical informatics making GBS valuable and reliable partner to any inter-disciplinary collaborative project.