This assay is based on RBL-2H3 cells, that like mast cells and basophils, undergo degranulation with release of a range of pre-formed and newly-synthesized mediators that induce a potent allergic response.

KEY APPLICATIONS:

This assay can primarily be used as a tool to assess allergenicity of biological compounds, cross-reactivity of food proteins, effect of processing on the allergenicity of proteins, or for initial screening of anti-allergic potential of new investigational products.

GBS experts can help with scientific as well as technical questions and while designing the assay the purpose of your study is always the main focus.